Neurogenic Heterotopic Ossifications Recapitulate Hematopoietic Stem Cell Niche Development Within an Adult Osteogenic Muscle Environment

Neurogenic Heterotopic Ossifications Recapitulate Hematopoietic Stem Cell Niche Development Within an Adult Osteogenic Muscle Environment

Hematopoiesis and bone interact in various developmental and pathological processes. Neurogenic heterotopic ossifications (NHO) are the formation of ectopic hematopoietic bones in peri-articular muscles that develop following severe lesions of the central nervous system such as traumatic cerebral or...

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Bibliographic Details
Main Authors: Dorothée Girard, Frédéric Torossian, Estelle Oberlin, Kylie A. Alexander, Jules Gueguen, Hsu-Wen Tseng, François Genêt, Jean-Jacques Lataillade, Marjorie Salga, Jean-Pierre Levesque, Marie-Caroline Le Bousse-Kerdilès, Sébastien Banzet
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
neurogenic heterotopic ossifications
ectopic hematopoietic niche
muscle environment
inflammation
macrophages
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.611842/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.611842/full

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