Replication of Salmonella enterica serovar Typhimurium in RAW264.7 Phagocytes Correlates With Hypoxia and Lack of iNOS Expression

Replication of Salmonella enterica serovar Typhimurium in RAW264.7 Phagocytes Correlates With Hypoxia and Lack of iNOS Expression

Salmonella infection associates with tissue hypoxia, while inducible nitric oxide synthase (iNOS), relying for its activity on molecular oxygen, stands as a central host defence measure in murine salmonellosis. Here, we have detailed hypoxia and iNOS responses of murine macrophage-like RAW264.7 cell...

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Bibliographic Details
Main Authors: Marie Wrande, Kim Vestö, Speranta Puiac Banesaru, Naeem Anwar, Johan Nordfjell, Lifeng Liu, Gerald M. McInerney, Mikael Rhen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Salmonella enterica
hypoxia
iNOS
macrophages
bacterial infection
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2020.537782/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2020.537782/full

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