Integrated weighted gene co-expression network analysis uncovers STAT1(signal transducer and activator of transcription 1) and IFI44L (interferon-induced protein 44-like) as key genes in pulmonary arterial hypertension

Integrated weighted gene co-expression network analysis uncovers STAT1(signal transducer and activator of transcription 1) and IFI44L (interferon-induced protein 44-like) as key genes in pulmonary arterial hypertension

Despite the multiple diagnostic and therapeutic strategies implemented in clinical practice, the mortality rate of patients with pulmonary arterial hypertension (PAH) remains high. Understanding the mechanisms and key genes involved could provide insight into the drivers of the pathogenesis of PAH....

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Bibliographic Details
Main Authors: Han Yang, Yang Lu, Hongmin Yang, Yaoxi Zhu, Yaohan Tang, Lixia Li, Changhu Liu, Jing Yuan
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Bioengineered
Subjects:
pulmonary arterial hypertension
stat1
ifi44l
gene expression
wgcna
Online Access:http://dx.doi.org/10.1080/21655979.2021.1972200

Internet

http://dx.doi.org/10.1080/21655979.2021.1972200

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