Estrogen receptors and their implications in colorectal carcinogenesis
Upon binding their cognate receptors, ERα (ESR1) and ERβ (ESR2), estrogens activate intracellular signaling cascades that have important consequences for cellular behavior. Historically linked to carcinogenesis in reproductive organs, estrogens have also been implicated in the pathogenesis of differ...
Main Authors: | Francesco eCaiazza, Elizabeth J Ryan, Glen eDoherty, Desmond C Winter, Kieran eSheahan |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-02-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00019/full |
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