Estrogen receptors and their implications in colorectal carcinogenesis

Estrogen receptors and their implications in colorectal carcinogenesis

Upon binding their cognate receptors, ERα (ESR1) and ERβ (ESR2), estrogens activate intracellular signaling cascades that have important consequences for cellular behavior. Historically linked to carcinogenesis in reproductive organs, estrogens have also been implicated in the pathogenesis of differ...

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Bibliographic Details
Main Authors: Francesco eCaiazza, Elizabeth J Ryan, Glen eDoherty, Desmond C Winter, Kieran eSheahan
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Oncology
Subjects:
Colorectal Neoplasms
Estrogen Receptor alpha
Estrogen Receptor beta
Estrogens
cancer therapeutics
tumor immunology
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00019/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00019/full

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