Inter-study and time-dependent variability of metabolite abundance in cultured red blood cells

Abstract Background Cultured human red blood cells (RBCs) provide a powerful ex vivo assay platform to study blood-stage malaria infection and propagation. In recent years, high-resolution metabolomic methods have quantified hundreds of metabolites from parasite-infected RBC cultures under a variety...

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Bibliographic Details
Main Authors: Shivendra G. Tewari, Krithika Rajaram, Russell P. Swift, Bobby Kwan, Jaques Reifman, Sean T. Prigge, Anders Wallqvist
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Malaria Journal
Subjects:
Online Access:https://doi.org/10.1186/s12936-021-03780-5