Hyperoxia disrupts pulmonary epithelial barrier in newborn rats via the deterioration of occludin and ZO-1

<p>Abstract</p> <p>Background</p> <p>Prolonged exposure to hyperoxia in neonates can cause hyperoxic acute lung injury (HALI), which is characterized by increased pulmonary permeability and diffuse infiltration of various inflammatory cells. Disruption of the epithelial...

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Bibliographic Details
Main Authors: You Kai, Xu Xuewen, Fu Jianhua, Xu Shuyan, Yue Xiaohong, Yu Zhiling, Xue Xindong
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Respiratory Research
Subjects:
Online Access:http://www.respiratory-research.com/content/13/1/36