Invariant Chain Complexes and Clusters as Platforms for MIF Signaling
Invariant chain (Ii/CD74) has been identified as a surface receptor for migration inhibitory factor (MIF). Most cells that express Ii also synthesize major histocompatibility complex class II (MHC II) molecules, which depend on Ii as a chaperone and a targeting factor. The assembly of nonameric comp...
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-02-01
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| Series: | Cells |
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| Online Access: | http://www.mdpi.com/2073-4409/6/1/6 |