Center or periphery? Modeling the effects of focal adhesion placement during cell spreading.

Focal adhesions are often observed at the cell's periphery. We provide an explanation for this observation using a system-level mathematical model of a cell interacting with a two-dimensional substrate. The model describes the biological cell as a hypoelastic continuum material whose behavior i...

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Bibliographic Details
Main Authors: Magdalena A Stolarska, Aravind R Rammohan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5291721?pdf=render