Emergent heterogeneity in putative mesenchymal stem cell colonies: Single-cell time lapsed analysis.

Bone marrow stromal cells (BMSCs) include a subset of stem cells that are considered promising for developmental studies and therapeutic applications. While it is appreciated generally that BMSC populations can exhibit morphological and functional heterogeneity upon in vitro culture expansion, the p...

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Bibliographic Details
Main Authors: Deena A Rennerfeldt, Joana S Raminhos, Samantha M Leff, Pristinavae Manning, Krystyn J Van Vliet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0213452