Neurotrophic growth factors for the treatment of amyotrophic lateral sclerosis: where do we stand ?

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that results in progressive loss of motoneurons, motor weakness and death within 3-5 years after disease onset. Therapeutic options remain limited despite substantial number of approaches that have been tested clinically....

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Bibliographic Details
Main Authors: Alexandre Henriques, Claudia Pitzer, Armin Schneider
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-06-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2010.00032/full