The Relationship between Skewed X-chromosome Inactivation and Neurological Disorders Development

X-chromosome inactivation (XCI) is a process by which one of the copies of the X chromosome in mammalian female cells is inactivated. The XCI causes a balanced X-linked gene quantity between male and females; moreover, it results mosaic females which have paternal active X in some cells and maternal...

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Bibliographic Details
Main Authors: Mahdi Taherian, Hossein Maghsoudi, Kazem Bidaki, Reza Taherian
Format: Article
Language:English
Published: Shahid Beheshti University of Medical Sciences 2016-04-01
Series:International Clinical Neuroscience Journal
Online Access:http://journals.sbmu.ac.ir/Neuroscience/article/download/13542/2