Fe-doped chrysotile nanotubes containing siRNAs to silence SPAG5 to treat bladder cancer

Fe-doped chrysotile nanotubes containing siRNAs to silence SPAG5 to treat bladder cancer

Abstract Background For certain human cancers, sperm associated antigen 5 (SPAG5) exerts important functions for their development and progression. However, whether RNA interference (RNAi) targeting SPAG5 has antitumor effects has not been determined clinically. Results The results indicated that Fe...

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Bibliographic Details
Main Authors: Jianye Liu, Yi Zhang, Hongliang Zeng, Long Wang, Qun Zhang, Pei Wu, Xiaoming Liu, Hongyi Xie, Wei Xiang, Biao Liu, Jiahao Liu, Xuewen Liu, Jianfei Xie, Jin Tang, Zhi Long, Leye He, Mengqing Xiao, Liang Xiang, Ke Cao
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Nanobiotechnology
Subjects:
Fe-doped chrysotile nanotubes
Gene therapy
Targeted delivery
SiRNA-SPAG5
Bladder cancer
Online Access:https://doi.org/10.1186/s12951-021-00935-z

Internet

https://doi.org/10.1186/s12951-021-00935-z

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