Mutations in neuroligin-3 in male mice impact behavioral flexibility but not relational memory in a touchscreen test of visual transitive inference

Mutations in neuroligin-3 in male mice impact behavioral flexibility but not relational memory in a touchscreen test of visual transitive inference

Abstract Cognitive dysfunction including disrupted behavioral flexibility is central to neurodevelopmental disorders such as Autism Spectrum Disorder (ASD). A cognitive measure that assesses relational memory, and the ability to flexibly assimilate and transfer learned information is transitive infe...

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Bibliographic Details
Main Authors: Rebecca H. C. Norris, Leonid Churilov, Anthony J. Hannan, Jess Nithianantharajah
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Molecular Autism
Subjects:
Autism spectrum disorder
Perseveration
Processing speed
Reaction time
Synapse
Online Access:https://doi.org/10.1186/s13229-019-0292-2

Internet

https://doi.org/10.1186/s13229-019-0292-2

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