Late Antiretroviral Therapy (ART) Initiation Is Associated with Long-Term Persistence of Systemic Inflammation and Metabolic Abnormalities.

HIV-induced immunodeficiency is associated with metabolic abnormalities and systemic inflammation. We investigated the effect of antiretroviral therapy (ART) on restoration of insulin sensitivity, markers of immune activation and inflammation.Immunological, metabolic and inflammatory status was asse...

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Main Authors: Mathilde Ghislain, Jean-Philippe Bastard, Laurence Meyer, Jacqueline Capeau, Soraya Fellahi, Laurence Gérard, Thierry May, Anne Simon, Corinne Vigouroux, Cécile Goujard, ANRS-COPANA Cohort Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4670073?pdf=render