Specific immediate early gene expression induced by high doses of salicylate in the cochlear nucleus and inferior colliculus of the rat

Abstract Introduction: Salicylate at high doses induces tinnitus in humans and experimental animals. However, the mechanisms and loci of action of salicylate in inducing tinnitus are still not well known. The expression of Immediate Early Genes (IEG) is traditionally associated with long-term neuro...

Full description

Bibliographic Details
Main Authors: Paula Santos, Lilian Eslaine Costa Mendes da Silva, Ricardo Maurício Leão
Format: Article
Language:English
Published: Elsevier
Series:Brazilian Journal of Otorhinolaryngology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942017000200155&lng=en&tlng=en