Marine Ligands of the Pregnane X Receptor (PXR): An Overview

Pregnane X Receptor (PXR) is a ligand-activated transcription factor which binds many structurally different molecules. The receptor is able to regulate the expression of a wide array of genes and is involved in cancer and different key physiological processes such as the metabolism of drugs/xenobio...

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Bibliographic Details
Main Authors: Alejandro Carazo, Přemysl Mladěnka, Petr Pávek
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Marine Drugs
Subjects:
pxr
Online Access:https://www.mdpi.com/1660-3397/17/10/554