APOOL is a cardiolipin-binding constituent of the Mitofilin/MINOS protein complex determining cristae morphology in mammalian mitochondria.

APOOL is a cardiolipin-binding constituent of the Mitofilin/MINOS protein complex determining cristae morphology in mammalian mitochondria.

Mitochondrial cristae morphology is highly variable and altered under numerous pathological conditions. The protein complexes involved are largely unknown or only insufficiently characterized. Using complexome profiling we identified apolipoprotein O (APOO) and apolipoprotein O-like protein (APOOL)...

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Bibliographic Details
Main Authors: Tobias A Weber, Sebastian Koob, Heinrich Heide, Ilka Wittig, Brian Head, Alexander van der Bliek, Ulrich Brandt, Michel Mittelbronn, Andreas S Reichert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3660581?pdf=render

Internet

http://europepmc.org/articles/PMC3660581?pdf=render

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