Antinociceptive Action of Isolated Mitragynine from Mitragyna Speciosa through Activation of Opioid Receptor System

Cannabinoids and opioids systems share numerous pharmacological properties and antinociception is one of them. Previous findings have shown that mitragynine (MG), a major indole alkaloid found in Mitragyna speciosa (MS) can exert its antinociceptive effects through the opioids system. In the present...

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Bibliographic Details
Main Authors: Mohamad Aris Mohd Moklas, Palanisamy Arulselvan, Ithnin Hairuszah, Mohamad Taufik Hidayat, Sharida Fakurazi, Abdul Rahman Shamima
Format: Article
Language:English
Published: MDPI AG 2012-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/13/9/11427