CD8+ T cells mediate the athero-protective effect of immunization with an ApoB-100 peptide.

CD8+ T cells mediate the athero-protective effect of immunization with an ApoB-100 peptide.

Immunization of hypercholesterolemic mice with selected apoB-100 peptide antigens reduces atherosclerosis but the precise immune mediators of athero-protection remain unclear. In this study we show that immunization of apoE (-/-) mice with p210, a 20 amino acid apoB-100 related peptide, reduced aort...

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Bibliographic Details
Main Authors: Kuang-Yuh Chyu, Xiaoning Zhao, Paul C Dimayuga, Jianchang Zhou, Xiaojun Li, Juliana Yano, Wai Man Lio, Lai Fan Chan, Jonathan Kirzner, Portia Trinidad, Bojan Cercek, Prediman K Shah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3276497?pdf=render

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http://europepmc.org/articles/PMC3276497?pdf=render

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