Effect of maraviroc intensification on HIV-1-specific T cell immunity in recently HIV-1-infected individuals.

The effect of maraviroc on the maintenance and the function of HIV-1-specific T cell responses remains unknown.Subjects recently infected with HIV-1 were randomized to receive anti-retroviral treatment with or without maraviroc intensification for 48 weeks, and were monitored up to week 60. PBMC and...

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Main Authors: Ai Kawana-Tachikawa, Josep M Llibre, Isabel Bravo, Roser Escrig, Beatriz Mothe, Jordi Puig, Maria C Puertas, Javier Martinez-Picado, Julia Blanco, Christian Manzardo, Jose M Miro, Aikichi Iwamoto, Anton L Pozniak, Jose M Gatell, Bonaventura Clotet, Christian Brander, MARAVIBOOST Investigators
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3903883?pdf=render