Osx-Cre targets multiple cell types besides osteoblast lineage in postnatal mice.

Osterix (Osx or Sp7) is a zinc-finger-family transcriptional factor essential for osteoblast differentiation in mammals. The Osx-Cre mouse line (also known as Osx1-GFP::Cre) expresses GFP::Cre fusion protein from a BAC transgene containing the Osx regulatory sequence. The mouse strain was initially...

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Bibliographic Details
Main Authors: Jianquan Chen, Yu Shi, Jenna Regan, Kannan Karuppaiah, David M Ornitz, Fanxin Long
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3893188?pdf=render