Berberine Regulates Treg/Th17 Balance to Treat Ulcerative Colitis Through Modulating the Gut Microbiota in the Colon

Berberine Regulates Treg/Th17 Balance to Treat Ulcerative Colitis Through Modulating the Gut Microbiota in the Colon

Berberine (BBR), an alkaloid isolated from Rhizoma Coptidis, Cortex Phellode, and Berberis, has been widely used in the treatment of ulcerative colitis (UC). However, the mechanism of BBR on UC is unknown. In this study, we investigated the activities of T regulatory cell (Treg) and T helper 17 cell...

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Bibliographic Details
Main Authors: Huantian Cui, Yuzi Cai, Li Wang, Beitian Jia, Junchen Li, Shuwu Zhao, Xiaoqian Chu, Jin Lin, Xiaoyu Zhang, Yuhong Bian, Pengwei Zhuang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Pharmacology
Subjects:
ulcerative colitis
berberine
gut microbiota
Treg/Th17 balance
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00571/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00571/full

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