Effects of (Pro)renin Receptor on Diabetic Cardiomyopathy Pathological Processes in Rats via the PRR-AMPK-YAP Pathway

Effects of (Pro)renin Receptor on Diabetic Cardiomyopathy Pathological Processes in Rats via the PRR-AMPK-YAP Pathway

Diabetic cardiomyopathy (DCM) is a common complication associated with diabetes. The (pro)renin receptor (PRR) is an important member of the local tissue renin-angiotensin system and plays a vital role in many cardiovascular diseases. Yes-associated protein (YAP) also plays a crucial role in many ca...

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Bibliographic Details
Main Authors: Jie Xiong, Xuefei Dong, Shengnan Li, Fan Jiang, Jing Chen, Shiran Yu, Bo Dong, Qing Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Physiology
Subjects:
diabetic cardiomyopathy
(pro)renin receptor
Yes-associated protein
AMPK
myocardial fibrosis
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.657378/full

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https://www.frontiersin.org/articles/10.3389/fphys.2021.657378/full

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