Altered gut microbiota and endocannabinoid system tone in obese and diabetic leptin-resistant mice: impact on apelin regulation in adipose tissue

Altered gut microbiota and endocannabinoid system tone in obese and diabetic leptin-resistant mice: impact on apelin regulation in adipose tissue

Growing evidence supports the role of gut microbiota in the development of obesity, type 2 diabetes and low-grade inflammation. The endocrine activity of adipose tissue has been found to contribute to the regulation of glucose homeostasis and low-grade inflammation. Among the key hormones produced b...

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Bibliographic Details
Main Authors: Lucie eGeurts, Vladimir eLazarevic, Muriel eDerrien, Amandine eEverard, Marie eVan Roye, Claude eKnauf, Philippe eValet, Myriam eGirard, Giulio G Muccioli, Patrice eFrancois, Willem M de Vos, Jacques eSchrenzel, Nathalie M Delzenne, Patrice D. eCani
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Inflammation
type 2 diabetes
LPS
endocannabinoid
Gut Microbiota
Apelin
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00149/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00149/full

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