Characterization of a BAC transgenic mouse expressing Krt19-driven iCre recombinase in its digestive organs.

Cytokeratin 19 (KRT19) protein is highly expressed in the epithelium of the gastrointestinal (GI) tract, hepatobiliary tissues, and pancreas of humans and mice. In the present study, we used an improved Cre (iCre) gene to enhance the efficiency of Cre expression in mammalian cells. We established a...

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Bibliographic Details
Main Authors: Tomohiro Kanayama, Hiroyuki Tomita, Nguyen Huy Binh, Yuichiro Hatano, Hitomi Aoki, Hideshi Okada, Akihiro Hirata, Yoshitaka Fujihara, Takahiro Kunisada, Akira Hara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0220818