HLA-E Polymorphism Determines Susceptibility to BK Virus Nephropathy after Living-Donor Kidney Transplant

HLA-E Polymorphism Determines Susceptibility to BK Virus Nephropathy after Living-Donor Kidney Transplant

Human leukocyte antigen (HLA)-E is important for the regulation of anti-viral immunity. BK polyomavirus (BKPyV) reactivation after kidney transplant is a serious complication that can result in BKPyV-associated nephropathy (PyVAN) and subsequent allograft loss. To elucidate whether HLA-E polymorphis...

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Bibliographic Details
Main Authors: Hana Rohn, Rafael Tomoya Michita, Sabine Schramm, Sebastian Dolff, Anja Gäckler, Johannes Korth, Falko M. Heinemann, Benjamin Wilde, Mirko Trilling, Peter A. Horn, Andreas Kribben, Oliver Witzke, Vera Rebmann
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
BK virus
polyomavirus
nephropathy
human leukocyte antigen-E
kidney transplantation
Online Access:https://www.mdpi.com/2073-4409/8/8/847

Internet

https://www.mdpi.com/2073-4409/8/8/847

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