Curcumin down-regulates DNA methyltransferase 1 and plays an anti-leukemic role in acute myeloid leukemia.

Curcumin down-regulates DNA methyltransferase 1 and plays an anti-leukemic role in acute myeloid leukemia.

Bioactive components from dietary supplements such as curcumin may represent attractive agents for cancer prevention or treatment. DNA methylation plays a critical role in acute myeloid leukemia (AML) development, and presents an excellent target for treatment of this disease. However, it remains la...

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Bibliographic Details
Main Authors: Jianhua Yu, Yong Peng, Lai-Chu Wu, Zhiliang Xie, Youcai Deng, Tiffany Hughes, Shun He, XiaoKui Mo, Ming Chiu, Qi-En Wang, Xiaoming He, Shujun Liu, Michael R Grever, Kenneth K Chan, Zhongfa Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3572185?pdf=render

Internet

http://europepmc.org/articles/PMC3572185?pdf=render

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