Does evaluation of in vitro microfilarial motility reflect the resistance status of Dirofilaria immitis isolates to macrocyclic lactones?

Does evaluation of in vitro microfilarial motility reflect the resistance status of Dirofilaria immitis isolates to macrocyclic lactones?

Abstract Background Several reports have confirmed that macrocyclic lactone-resistant isolates of Dirofilaria immitis are circulating in the United States; however, the prevalence and potential impact of drug resistance is unknown. We wished to assess computer-aided measurements of motility as a met...

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Bibliographic Details
Main Authors: Mary J. Maclean, Molly D. Savadelis, Ruby Coates, Michael T. Dzimianski, Corey Jones, Cynthia Benbow, Bobby E. Storey, Ray M. Kaplan, Andrew R. Moorhead, Adrian J. Wolstenholme
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Parasites & Vectors
Subjects:
Heartworm
Drug resistance
Macrocyclic lactones
Ivermectin
Microfilarial motility
Online Access:http://link.springer.com/article/10.1186/s13071-017-2436-6

Internet

http://link.springer.com/article/10.1186/s13071-017-2436-6

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