Identification and Characterization of an Anti-Fibrotic Benzopyran Compound Isolated from Mangrove-Derived Streptomyces xiamenensis

Identification and Characterization of an Anti-Fibrotic Benzopyran Compound Isolated from Mangrove-Derived Streptomyces xiamenensis

An anti-fibrotic compound produced by Streptomyces xiamenensis, found in mangrove sediments, was investigated for possible therapeutic effects against fibrosis. The compound, N-[[3,4-dihydro-3S-hydroxy-2S-methyl-2-(4¢R-methyl-3¢S-pentenyl)-2H-1-benzopyran-6-yl]carbonyl]-threonine (1), was isolated f...

Full description

Bibliographic Details
Main Authors: Jun Xu, Song-Lin Yang, Zhi-Gang Zhang, Ping Ao, Wen-Han Lin, Dong Liu, Zhen-Hao Xu, Xiao-Meng Lang, Yi-Lei Zhao, Min-Juan Xu, Xiao-Jin Liu
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:Marine Drugs
Subjects:
Streptomyces xiamenensis
mangrove
benzopyran
fibroblast
anti-fibrosis
anti-contractile capacity
Online Access:http://www.mdpi.com/1660-3397/10/3/639/

Internet

http://www.mdpi.com/1660-3397/10/3/639/

Similar Items