Enantioselective Synthesis of Acyclic Orthogonally Functionalized Compounds Bearing a Quaternary Stereocenter Using Chiral Ammonium Salt Catalysis

Abstract We herein report an asymmetric protocol to access a series of orthogonally functionalized acyclic chiral target molecules containing a quaternary stereogenic center by carrying out the enantioselective α‐alkylation of novel orthogonally functionalized dioxolane‐containing cyanoacetates unde...

Full description

Bibliographic Details
Main Authors: Katharina Röser, Bettina Berger, Prof. Michael Widhalm, Prof. Mario Waser
Format: Article
Language:English
Published: Wiley-VCH 2021-08-01
Series:ChemistryOpen
Subjects:
Online Access:https://doi.org/10.1002/open.202100162