Nebulisation of IVT mRNA Complexes for Intrapulmonary Administration.

During the last years the potential role of in vitro transcribed (IVT) mRNA as a vehicle to deliver genetic information has come into focus. IVT mRNA could be used for anti-cancer therapies, vaccination purposes, generation of pluripotent stem cells and also for genome engineering or protein replace...

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Bibliographic Details
Main Authors: Sarah M Johler, Joanna Rejman, Shan Guan, Joseph Rosenecker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4564175?pdf=render