‘High vault-age’: non-coding RNA control of autophagy

RNA-binding proteins typically change the fate of RNA, such as stability, translation or processing. Conversely, we recently uncovered that the small non-coding vault RNA 1-1 (vtRNA1-1) directly binds to the autophagic receptor p62/SQSTM1 and changes the protein's function. We refer to this pro...

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Bibliographic Details
Main Authors: Magdalena Büscher, Rastislav Horos, Matthias W. Hentze
Format: Article
Language:English
Published: The Royal Society 2020-02-01
Series:Open Biology
Subjects:
p62
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.190307