TAp73β Can Promote Hepatocellular Carcinoma Dedifferentiation

TAp73β Can Promote Hepatocellular Carcinoma Dedifferentiation

Hepatocyte dedifferentiation is a major source of hepatocellular carcinoma (HCC), but its mechanisms are unknown. We explored the p73 expression in HCC tumors and studied the effects of transcriptionally active p73β (TAp73β) in HCC cells. Expression profiles of p73 and patient clinical data were col...

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Bibliographic Details
Main Authors: Evin Iscan, Umut Ekin, Gokhan Yildiz, Ozden Oz, Umur Keles, Aslı Suner, Gulcin Cakan-Akdogan, Gunes Ozhan, Marta Nekulova, Borivoj Vojtesek, Hamdiye Uzuner, Gökhan Karakülah, Hani Alotaibi, Mehmet Ozturk
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
TAp73
hepatocellular carcinoma
metastasis
dedifferentiation
zebrafish
yes-associated protein 1
Online Access:https://www.mdpi.com/2072-6694/13/4/783

Internet

https://www.mdpi.com/2072-6694/13/4/783

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