Corneal oxidative damage in keratoconus cells due to decreased oxidant elimination from modified expression levels of SOD enzymes, PRDX6, SCARA3, CPSF3, and FOXM1

Corneal oxidative damage in keratoconus cells due to decreased oxidant elimination from modified expression levels of SOD enzymes, PRDX6, SCARA3, CPSF3, and FOXM1

Purpose: To compare the levels of gene expression for enzymes involved in production and elimination of reactive oxygen/nitrogen species (ROS/RNS) in normal human corneal cells (NL cells) with those in human corneal cells with keratoconus (KC cells) in vitro. Methods: Primary NL and KC stromal fibr...

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Bibliographic Details
Main Authors: Shari R Atilano, Daniel H Lee, Paula S Fukuhara, Marilyn Chwa, Anthony B Nesburn, Nitin Udar, Cristina Kenney
Format: Article
Language:English
Published: Knowledge E 2019-01-01
Series:Journal of Ophthalmic & Vision Research
Subjects:
CPSF3; FOXM1; Keratoconus; PRDX6; SCARA3; SOD
Online Access:http://www.jovr.org/article.asp?issn=2008-322X;year=2019;volume=14;issue=1;spage=62;epage=70;aulast=Atilano

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http://www.jovr.org/article.asp?issn=2008-322X;year=2019;volume=14;issue=1;spage=62;epage=70;aulast=Atilano

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