Corneal oxidative damage in keratoconus cells due to decreased oxidant elimination from modified expression levels of SOD enzymes, PRDX6, SCARA3, CPSF3, and FOXM1

Purpose: To compare the levels of gene expression for enzymes involved in production and elimination of reactive oxygen/nitrogen species (ROS/RNS) in normal human corneal cells (NL cells) with those in human corneal cells with keratoconus (KC cells) in vitro. Methods: Primary NL and KC stromal fibr...

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Bibliographic Details
Main Authors: Shari R Atilano, Daniel H Lee, Paula S Fukuhara, Marilyn Chwa, Anthony B Nesburn, Nitin Udar, Cristina Kenney
Format: Article
Language:English
Published: Knowledge E 2019-01-01
Series:Journal of Ophthalmic & Vision Research
Subjects:
Online Access:http://www.jovr.org/article.asp?issn=2008-322X;year=2019;volume=14;issue=1;spage=62;epage=70;aulast=Atilano