Synthesis and evaluation of anti-leishmania activity of analogs isoxazoles derivatives of grandisin and veraguensin neolignans
<em>Using the concept of bioisosterismo, the new analogs isoxazole were designed from the molecular modification of grandisin and veraguensin neolignans, which have a grouping that is a furan ring bioisóstero isoxazole. In order to obtain more potent compounds, and better physical and chemical...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Universidade Federal de Mato Grosso do Sul
2012-06-01
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Series: | Orbital: The Electronic Journal of Chemistry |
Subjects: | |
Online Access: | http://orbital.ufms.br/index.php/Chemistry/article/view/374 |