Profiles of multidrug resistance protein-1 in the peripheral blood mononuclear cells of patients with refractory epilepsy.

BACKGROUND: About one third of patients with epilepsy become refractory to therapy despite receiving adequate medical treatment, possibly from multidrug resistance. P-glycoprotein, encoded by multidrug resistance protein-1 (MDR1) gene, at the blood brain barrier is considered as a major factor media...

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Main Authors: Jae-Jun Ban, Keun-Hwa Jung, Kon Chu, Soon-Tae Lee, Daejong Jeon, Kyung-Il Park, Hye-Jin Moon, Hyeyun Kim, Sunghun Kim, Sang Kun Lee, Jae-Kyu Roh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3351424?pdf=render