Extracellular detection of neuronal coupling

Abstract We developed a method to non-invasively detect synaptic relationships among neurons from in vitro networks. Our method uses microelectrode arrays on which neurons are cultured and from which propagation of extracellular action potentials (eAPs) in single axons are recorded at multiple elect...

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Bibliographic Details
Main Authors: Elmer Guzman, Zhuowei Cheng, Paul K. Hansma, Kenneth R. Tovar, Linda R. Petzold, Kenneth S. Kosik
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94282-6