Antibacterial polymer nanofiber-coated and high elastin protein-expressing BMSCs incorporated polypropylene mesh for accelerating healing of female pelvic floor dysfunction

Antibacterial polymer nanofiber-coated and high elastin protein-expressing BMSCs incorporated polypropylene mesh for accelerating healing of female pelvic floor dysfunction

To solve the bio-inertness of widely used polypropylene (PP) mesh for treating pelvic floor dysfunction (PFD), a novel strategy of incorporation with elastin gene-transfected bone marrow stem cells (BMSCs) and antibacteria drug-loaded polylactic acid (PLA) nanofibrous mat covering layer was proposed...

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Bibliographic Details
Main Authors: Liu Min, Wang Lei, Tong Xiaowen, Dai Jiamu, Li Guang, Zhang Peihua, Li Huaifang
Format: Article
Language:English
Published: De Gruyter 2020-08-01
Series:Nanotechnology Reviews
Subjects:
antibacteria nanofiber-coated polypropylene mesh
pelvic floor reconstruction
elastin gene transfection
Online Access:https://doi.org/10.1515/ntrev-2020-0052

Internet

https://doi.org/10.1515/ntrev-2020-0052

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