YopE specific CD8+ T cells provide protection against systemic and mucosal Yersinia pseudotuberculosis infection.

Prior studies indicated that CD8+ T cells responding to a surrogate single antigen expressed by Y. pseudotuberculosis, ovalbumin, were insufficient to protect against yersiniosis. Herein we tested the hypothesis that CD8+ T cells reactive to the natural Yersinia antigen YopE would be more effective...

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Bibliographic Details
Main Authors: Norberto González-Juarbe, Haiqian Shen, Molly A Bergman, Carlos J Orihuela, Peter H Dube
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5313184?pdf=render