Single Domain Antibody Fragments as Drug Surrogates Targeting Protein–Protein Interactions inside Cells

Many human diseases are caused by mutant or abnormal protein functions that are largely confined to the inside of cells, rather than being displayed on the abnormal cell surface. Furthermore, many of the functional consequences of aberrant proteins, such as in cancer cells, are due to protein–protei...

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Bibliographic Details
Main Authors: Terence H. Rabbitts, Jing Zhang, Tomoyuki Tanaka, Jia Zeng
Format: Article
Language:English
Published: MDPI AG 2013-05-01
Series:Antibodies
Subjects:
VH
PPI
Online Access:http://www.mdpi.com/2073-4468/2/2/306