Regulation of HGF Expression by ΔEGFR-Mediated c-Met Activation in Glioblastoma Cells

Regulation of HGF Expression by ΔEGFR-Mediated c-Met Activation in Glioblastoma Cells

The hepatocyte growth factor receptor (c-Met) and a constitutively active mutant of the epidermal growth factor receptor (ΔEGFR/EGFRvIII) are frequently overexpressed in glioblastoma (GBM) and promote tumorigenesis. The mechanisms underlying elevated hepatocyte growth factor (HGF) production in GBM...

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Bibliographic Details
Main Authors: Jeannine Garnett, Vaibhav Chumbalkar, Brian Vaillant, Anupama E. Gururaj, Kristen S. Hill, Khatri Latha, Jun Yao, Waldemar Priebe, Howard Colman, Lisa A. Elferink, Oliver Bogler
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558613801273

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http://www.sciencedirect.com/science/article/pii/S1476558613801273

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