High-fat-diet-induced weight gain ameliorates bone loss without exacerbating AβPP processing and cognition in female APP/PS1 mice

High-fat-diet-induced weight gain ameliorates bone loss without exacerbating AβPP processing and cognition in female APP/PS1 mice

Osteoporosis is negatively correlated with body mass, whereas both osteoporosis and weight loss occur at higher incidence during the progression of Alzheimer’s disease (AD) than the age-matched non-dementia individuals. Given that there is no evidence that overweight associated with AD-type cognitiv...

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Bibliographic Details
Main Authors: Yunhua ePeng, Jing eLiu, Ying eTang, Jianshu eLiu, Tingting eHan, Shujun eHan, Hua eLi, Chen eHou, Jiankang eLiu, Jiangang eLong
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Leptin
Osteoporosis
Weight Gain
Alzheimer’s disease
bone mineral density
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00225/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00225/full

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