Benchmarking cryo-EM Single Particle Analysis Workflow

Benchmarking cryo-EM Single Particle Analysis Workflow

Cryo electron microscopy facilities running multiple instruments and serving users with varying skill levels need a robust and reliable method for benchmarking both the hardware and software components of their single particle analysis workflow. The workflow is complex, with many bottlenecks existin...

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Bibliographic Details
Main Authors: Laura Y. Kim, William J. Rice, Edward T. Eng, Mykhailo Kopylov, Anchi Cheng, Ashleigh M. Raczkowski, Kelsey D. Jordan, Daija Bobe, Clinton S. Potter, Bridget Carragher
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
cryo-electron microscopy
benchmarking
alignment
structural biology
single particle workflow
resolution
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2018.00050/full

Internet

https://www.frontiersin.org/article/10.3389/fmolb.2018.00050/full

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