Oxidized low density lipoprotein inhibits macrophage apoptosis through activation of the PI 3-kinase/PKB pathway

Oxidized low density lipoprotein inhibits macrophage apoptosis through activation of the PI 3-kinase/PKB pathway

Oxidized LDL (oxLDL) is known to induce endothelial adhesion molecule and monocyte chemoattractant protein 1 expression and this is thought to be involved in monocyte recruitment into atherosclerotic lesions. oxLDL has also been found to induce macrophage proliferation. The purpose of the present st...

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Bibliographic Details
Main Authors: Rajinder S. Hundal, Baljinder S. Salh, John W. Schrader, Antonio Gómez-Muñoz, Vincent Duronio, Urs P. Steinbrecher
Format: Article
Language:English
Published: Elsevier 2001-09-01
Series:Journal of Lipid Research
Subjects:
atherosclerosis
oxidized lipoproteins
M-CSF
signal transduction
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520302820

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http://www.sciencedirect.com/science/article/pii/S0022227520302820

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