CENP-A Subnuclear Localization Pattern as Marker Predicting Curability by Chemoradiation Therapy for Locally Advanced Head and Neck Cancer Patients

CENP-A Subnuclear Localization Pattern as Marker Predicting Curability by Chemoradiation Therapy for Locally Advanced Head and Neck Cancer Patients

Effective biomarkers predictive of the response to treatments are key for precision medicine. This study identifies the staining pattern of the centromeric histone 3 variant, CENP-A, as a predictive biomarker of locoregional disease curability by chemoradiation therapy. We compared by imaging the su...

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Bibliographic Details
Main Authors: Pierre Verrelle, Didier Meseure, Frédérique Berger, Audrey Forest, Renaud Leclère, André Nicolas, Emilie Fortas, Xavier Sastre-Garau, Marick Lae, Sabah Boudjemaa, Rodrigue Mbagui, Valentin Calugaru, Dalila Labiod, Leanne De Koning, Geneviève Almouzni, Jean-Pierre Quivy
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
biomarker
head and neck cancer
chemoradiation therapy
histological imaging
chromatin and nuclear organization
Online Access:https://www.mdpi.com/2072-6694/13/16/3928

Internet

https://www.mdpi.com/2072-6694/13/16/3928

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