Distinct contributions of hyperglycemia and high-fat feeding in metabolic syndrome-induced neuroinflammation

Distinct contributions of hyperglycemia and high-fat feeding in metabolic syndrome-induced neuroinflammation

Abstract Background High-fat feeding and hyperglycemia, key risk factors for the development of metabolic syndrome (MetS), are emerging to associate with increased risk of developing dementia and cognitive decline. Despite this, clinical and experimental studies have yet to elucidate the specific co...

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Bibliographic Details
Main Authors: Brooke J. Wanrooy, Kathryn Prame Kumar, Shu Wen Wen, Cheng Xue Qin, Rebecca H. Ritchie, Connie H. Y. Wong
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Journal of Neuroinflammation
Subjects:
Neuroinflammation
High-fat feeding
Microglia
Astrocytes
Hippocampus
Streptozotocin
Online Access:http://link.springer.com/article/10.1186/s12974-018-1329-8

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http://link.springer.com/article/10.1186/s12974-018-1329-8

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