Exploratory trials, confirmatory observations: A new reasoning model in the era of patient-centered medicine

<p>Abstract</p> <p>Background</p> <p>The prevailing view in therapeutic clinical research today is that observational studies are useful for generating new hypotheses and that controlled experiments (i.e., randomized clinical trials, RCTs) are the most appropriate metho...

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Bibliographic Details
Main Author: Sacristán José A
Format: Article
Language:English
Published: BMC 2011-04-01
Series:BMC Medical Research Methodology
Online Access:http://www.biomedcentral.com/1471-2288/11/57