Regulation of B cell responses by distinct populations of CD4 T cells

Maturation of B cells in Germinal Centers (GC) is a hallmark in adaptive immunity and the basis of successful vaccines that protect us against lethal infections. Nonetheless, vaccination efficacy is very much reduced in aged population and against highly mutagenic viruses. Therefore, it is key to un...

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Bibliographic Details
Main Authors: Meryem Aloulou, Nicolas Fazilleau
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Biomedical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2319417019304822